Sonia Michael Najjar, MS, PhD

教育:

• 生理学(博士), Stanford University Medical School, 1989
• 化学(女士), San Francisco State University, 1983
• 生物化学(BA), San Francisco State University, 1980

专业知识: 

• 胰岛素信号传导
• 胰岛素的间隙
• 胰岛素分泌
• 胰岛素代谢
• 胰岛素抵抗
• 脂质代谢
• 新生脂肪生成
• Adipocyte-hepatocyte axis
• Diet-induced insulin resistance
• 肥胖
• 2型糖尿病
• Non-alcoholic fatty liver disease (非酒精性脂肪肝/NASH)
• 肝纤维化
• 动脉粥样硬化
• Role of altered lipid metabolism in cancer

工作总结: 

Prof Najjar is best recognized for identifying a key role for hepatic insulin clearance in insulin action and fat metabolism, and how reduced insulin clearance causes insulin resistance, 肥胖, 非酒精性脂肪肝, 和动脉粥样硬化. She pioneered the finding that insulin acutely reduces fatty acid synthesis as opposed to its known chronic lipogenic action.

链接: 

View My Work in the National Center for Biotechnology Information (NCBI):

 http://www.ncbi.nlm.国家卫生Institutes.gov/myncbi/sonia.najjar.2/bibliography/public/